Active Constituents: Levamisole hydrochloride 10 mg/mL, praziquantel 2 mg/mL.

Avitrol Plus is a complete in water allwormer for birds.

• Treats, threadworm (Capillaria sp.), caecal worm (Heterakis sp.), roundworm (Ascaridia sp.), gape worm (Syngamus sp.), gizzard worm (Acuaria sp.) and tapeworm (Raillietina sp.) in ornamental cage birds.
• The major mode of action of levamisole is on the cholinergic receptor of the neuromuscular junction, causing paralysis of the parasite.
• Levamisole has been shown to inhibit fumarate reductase and to affect the rate of incorporation of glucose into glycogen.
• Praziquantel is a highly specific cestocidal drug that acts by damaging the tegument, inhibiting glucose uptake and stimulating lactate release.
• Tapeworms are destroyed in situ.
• Solution should be freshly made up before dosing.
• Repeat in 14 days with fresh solution, or as directed by a veterinary surgeon.

Dose:

Water dosage: .016 floz (0.5ml) per .676 floz (20mls) of drinking water, given fresh every 24 hrs, or .845 floz (25mls) per .264 gal (1 litre) of drinking water. Take all other source of drinking water out of the cage.

Crop dosage: a crop needle or tube placed directly into the crop can be used to administer Avitrol Plus syrup by syringe.

• Do not administer any liquid into the crop unless you are confident that the crop needle or tube is correctly placed.
• Use this as the sole source of drinking water for 24 hours and feed only seed, then replace with fresh clean water.

Contraindications and precautions:   species or strains of birds known to be sensitive to the effects of levamisole.

• Not recommended for use in Gouldian Finches.
• Precautions Parrots appear to be less tolerant than pigeons to levamisole.
• Do not dose in extremely hot, dry weather or treat stressed birds, or birds that are feeding young.
• Harmful if swallowed.
• Avoid contact with eyes and skin.
• Wash hands after use.

Adverse reactions and side effects: include regurgitation (which is not considered to be harmful), incoordination, leg and wing paresis. Deaths of birds up to 2 days after dosing have been attributed to obstruction from massive roundworm infestation.